RNA Polymerase II in Eukaryotes and Prokaryotes
by Bchm465 RNAP Group:
Siobhan Webb
Lisa Witte
Kitty Wong
Tinsay Woreta
Estelle Yoo
Description of this Website
This site
attempts to provide an overview of eukaryotic transcription machinery,
particularly the RNA Polymerase II. This Website contains information
on the general transcription factors, subunits, and mediator. It will
also discuss a proposed scheme for the transcription complex stability.
In addition, this site contains a comparison between the prokaryotic and
eukaryotic RNA Polymerase II.
The Machinery
RNA Polymerase II machinery
Adopted from
http://nsm1.utdallas.edu/bio/Dejong/dej99.html
RNA Polymerase II is the major enzyme responsible for transcription
of mRNA from a DNA template strand. The transcription machinery pictured
above illustrates the mechanism that works in concert with activators,
repressors, cofactors(mediators), general transcription factors (GTF),
and the RNA Polymerase II (RNAP II)
Discovery
Enzyme
Subunits
Mediator
General Transcripton Factors
RNAP Transcription Complex
Stability
Comparison of Bacterial
RNAP and Eukaryotic RNAP II
Works Cited
Mail Authors
Siobhan, Lisa, Kitty, Tinsay, Estelle
Copyrighted 2002 by Bchm465 RNAP Group.
Last updated May 8, 2002.