Molecular visualization of real B-form DNA


This set of web pages uses the open-source Java Applet program Jmol, a proposed platform-independent replacement for Chime and Rasmol, neither of which is available in an OS X native version. You will need a relatively recent Java Virtual Machine to use it. Currently the page runs Jmol 11.4.5.

Here is the color coding scheme used in many of the scripts:

Major groove -- red
Minor groove -- yellow
Watson-Crick H-bonding face -- blue
major groove and WC face -- purple
major groove and WC face -- green
backbone -- white, with orange P atoms
other atoms -- brown. Sugar protons not shown.
imino protons -- pink

The buttons below the Jmol window are generally intended to be clicked in order. There are some glitches if you show/hide waters. For more sophisticated commands, bring up a console window with a right-click/control click in the Jmol window.

The list on the right takes you to each of the other Jmol pages in the DNA/RNA tutorial.If your screen is large enough, use the "big" pages.

Go to small ideal B-DNA

Go to big ideal B-DNA

This is real B-DNA from Loren Williams group, PDB ID 355D. Note that it is not perfect B-form: groove widths vary, base pairs roll and tilt, there are several buckled or propellor-twisted base pairs.The "NMR" view isn't shown, because as an X-ray structure this has no hydrogens.The green base step showcases one with large roll. This page shows a view generated in Pymol similar to the final rendering, emphasizing the spine of hydration/sodium.

Go to big real B-DNA

Go to big ideal A-RNA

Go to small ideal A-RNA


DNA/RNA tutorial home. Teaching resources. J. Kahn home page.