Biochemistry 674: Biochemistry of Nucleic Acids
Class time: 8 a.m. TuTh, Chem 0127
Office Hours: Mon. 1:00-2:00, Thurs. 1:00-2:00 Chem 2500A
- Diagrams sketching (1) replication-mediated homologous recombination and (2) recombination-mediated
repair of replication forks are available under General Teaching Resources.
- Review session for the final will be December 15, 6:30-8:00 p.m., Chemistry
1402. The final will be December 17 at 10:30 a.m.
- Results from Exam 2. The key is on reserve.
- The paper topics deadline has been moved to November 18, and the papers
are due Dec. 9.
- Results from Exam 1. The key is on reserve.
- Study questions for required papers (updated
to include through Berns et al., 2005 and Park et al., 2002). One or two of the questions on these
last two papers will appear in substantially identical form on the final.
- General Teaching Resources, including an animation of
the growth of a helix from a base pair.
- Some old Exams I and II and finals.Answers
are on reserve in the libraryas usual.
- This year's syllabus (PDF).
- A Protein-DNA tutorial
using Rasmol on the HTH, ZnF, bZIP, and TBP DNA binding domain motifs and
their interactions with DNA.
- A DNA tutorial on the
structures of A and B form nucleic acids. This may require you to look at
the discussion of how
to run Rasmol from your computer.
- A large collection of
PDB files of RNA, DNA, RNA/DNA binding proteins, and protein-RNA/DNA
complexes, downloaded from the Protein
Data Bank Web site.
- A lot more info on groove-binding drugs and many other structures, at the
and Wemmer lab.
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Last Modified 9/10/01