Molecular visualization of a real protein alpha helix binding DNA

This web page uses the open-source Java Applet program Jmol. You will need a relatively recent Java Virtual Machine to use it and you will also have to jump through a lot of hoops to get your Mac to be willing to run a Java applet. Google for "run Java on <your platform here>"

The buttons below are generally intended to be clicked in order.

This shows the same alpha helix that we saw idealized before, now as part of a left-handed coiled coil that binds DNA, in the GCN4-DNA cocrystal structure 1YSA.

 

The idealized helix.

Click here for the beta sheet.

Click here for the idealized beta sheet.

Click here for the same beta sheet in the protein tendamistat.
Teaching resources. J. Kahn home page.