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Ashton Cropp

Ashton Cropp
Assistant Professor

acropp@mail.umd.edu
phone: 301.405.1734
fax: 301.314.9121

Chem. and Biochem. web site

Research Summary

Combinatorial design of natural products biosynthesis, bioorganic chemistry, protein engineering, synthetic biology and the evolution of new cellular function.

Recent Publications

Cropp, T.A. and Schultz P.G. 2004. An expanding genetic code. Trends in Genetics. In Press.

Wu, N., Deiters, A., Cropp, T.A., Bursulaya, B., King, D., Schultz, P.G. 2004. A genetically encoded photocaged amino acid. J. Am. Chem. Soc. In Press.

Chin J.W., Cropp T.A., Anderson J.C., Mukerji, M., Zhang Z., and Schultz P.G. 2003. An expanded eukaryotic genetic code. Science. 301: 964-7.

Deiters A., Cropp, T.A., Mukerji, M., Chin, J.W., Anderson J.C., and Schultz P.G. 2003. Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae. J. Am. Chem. Soc.125:11782-3.

Cropp, T.A., Wilson, D.J., and Reynolds, K.A. 2000. Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin. Nat. Biotechnol.18(9):980-83

Kim, B.S., Cropp, T.A., Florova, G., Lindsay, Y., Sherman, D.H., and Reynolds, K.A. 2002. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis. Biochemistry 41(35):10827-33.

 

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